How does FDG-PET compare to whole-body MRI in lymphoma disease?

Wayne Forrest
Nov 15, 2010

Sunday, November 28 | 11:15 a.m.-11:25 a.m. | SSA18-04 | Room S505AB
Italian researchers will answer that question at RSNA 2010 in Chicago, when they present their study results showing that whole-body MRI is fast and feasible for staging and restaging lymphoma disease; however, the modality falls short in matching the accuracy of FDG-PET/CT.

The study, co-authored by Carmelo Cicciò, MD, from the University of Rome "Tor Vergata," included 32 patients with proven cases of Hodgkin's lymphoma (14 patients) and non-Hodgkin's lymphoma (18 patients) who underwent whole-body MRI within one week from contrast-enhanced FDG-PET/CT.

The results showed that FDG-PET/CT correctly diagnosed 92 nodal regions as positive for lymphomatous involvement, and 458 nodal regions were determined to be disease-free. Whole-body MRI diagnosed 75 nodal regions as positive for lymphomatous involvement and 450 nodal regions as disease-free.

FDG-PET/CT also outperformed whole-body MRI in sensitivity, specificity, and accuracy.

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