Multiparametric MRI is increasingly used in the diagnostic pathway for prostate cancer, and it's also used with CAD systems designed to help radiologists detect and localize the disease, said Simone Mazzetti, PhD, from the Institute for Cancer Research and Treatment at Candiolo.
The researchers sought to develop a CAD system that could objectively analyze multiple MRI sequences and yield a malignancy probability map of the prostate on a pixel-wide basis, Mazzetti said.
Their CAD software, which is based on analysis of T2-weighted imaging and diffusion-weighted and dynamic contrast-enhanced acquisitions, was objective and reproducible in the study, according to the researchers.
It provides "unique information for clinicians, summarized in a malignancy probability map that will improve the diagnostic accuracy of the radiologist, reducing reader variability and speeding up the reading time," Mazzetti said.
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