The new guidance updates the task force's previous 2016 recommendation and finalizes a draft recommendation it issued last October. In it, the USPSTF gives a "B" designation ("high certainty that net benefit is moderate to substantial") for colorectal cancer screening in adults between the ages of 45 and 49, and an "A" designation ("high certainty that net benefit is substantial") for adults between the ages of 50 and 75. Adults over 75 should consult with their clinician about regular colon cancer screening, the task force said.
Colon cancer screening is performed with stool-based tests but also with CT colonography (CTC), which through literature review the USPSTF found to have a sensitivity for lesions 10 mm or larger ranging from 89% to 95% and a specificity of 89%.
The American College of Radiology (ACR) lauded the new guidance.
"[This new] recommendation for such screening in adults 45 to 49 means that millions more Americans will receive private insurance coverage for this vital screening," said Dr. Judy Yee, chair of the ACR's colon cancer committee, in a statement released by the college. "Expanded coverage will help medical providers save more lives ... Now Medicare must follow the USPSTF lead and cover beneficiaries for this lifesaving exam."
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