ACRIN study 6659, MR Imaging and MR Spectroscopic Imaging of Prostate Cancer Prior to Radical Prostatectomy, found that the accuracy of combined 1.5-tesla endorectal MRI and magnetic spectroscopic imaging is equal to that of MRI alone. The study was published in the April 2009 issue of Radiology.
From February 2004 to June 2005, 134 participants with biopsy-proved prostate cancer who were scheduled to undergo radical prostatectomy were enrolled from seven sites in the U.S. When the study was completed, ACRIN convened a panel to correlate the MRI images and MRSI data with histopathologic specimen data that served as the reference standard.
Although this combined imaging technique held significant promise, the data analysis did not confirm the trial's primary hypothesis of combined MRI/MRSI performing better than MRI alone, ACRIN said.
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