November 3, 2015 --
In their study, Kyle McMillan and colleagues from the Mayo Clinic in Rochester, MN, wanted to know if SSDE remained a valid measurement in the face of automated tube current modulation -- a development that could affect CT dose index volume (CTDIvol).
"In a previous paper, it was asserted that the concept of CTDIvol breaks down mathematically when tube current modulation is used," wrote study co-author Cynthia McCollough, PhD, in an email to AuntMinnie.com. "Since SSDE relies on CTDIvol and most modern body imaging is performed with the use of tube current modulation, this could affect the accuracy of SSDE calculations."
The study, performed with a 128-detector-row scanner, aimed to use previously validated Monte Carlo methods to determine the accuracy of SSDE, which represents the mean dose in the center of the scan region.
The results showed strong correlation between CTDIvol-normalized effective dose and water-equivalent diameter, according to the researchers. A general relationship between CTDIvol-to-effective-dose conversion coefficients and patient size is likely sufficient to estimate SSDE for exams acquired with both fixed and modulated tube currents.