Carestream gets FDA nod for bone-removal software

AuntMinnie.com staff writers

Apr 1, 2014

The U.S. Food and Drug Administration (FDA) has given 510(k) clearance to Carestream Health for a bone-suppression software feature for its computed and digital radiography systems.

The optional feature creates a companion image from the original exposure that can improve the visibility of lung nodules and other pathology by suppressing the appearance of ribs and clavicles. The software is available worldwide, according to Carestream.

The current version already offers companion images that can enhance the visibility of tubes, peripherally inserted central catheter (PICC) lines, and pneumothorax, the company said.

In addition, the software's new Integrating the Healthcare Enterprise (IHE) Dose Reporting capability will gather radiation dose information via the IHE profile and direct the information to a PACS.

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Test set images with ground truth (teal, red) and model predictions (green, yellow), with true positives (green), false positives (yellow), and false negatives (red). Predictions from the 6x-YOLOv5 ensemble trained on histogram equalized input images with a y = 0.2 avalanche scheme, achieving 0.536 precision, 0.795 recall, and 0.723 F2 score. Image and caption courtesy of Scientific Reports.

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Test set images with ground truth (teal, red) and model predictions (green, yellow), with true positives (green), false positives (yellow), and false negatives (red). Predictions from the 6x-YOLOv5 ensemble trained on histogram equalized input images with a y = 0.2 avalanche scheme, achieving 0.536 precision, 0.795 recall, and 0.723 F2 score. Image and caption courtesy of Scientific Reports.

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(a) Raw example of a dynamic digital radiograph. (b) Contrast equalization using contrast-limited adaptive equalization shows improved anatomical visualization. (c) Training data is generated through manually labeling using SLEAP’s graphical user interface. (d-e) Neural network detection schematic. For each quadrant a series of two networks were used. The first identifies the quadrant center, the second using input of the first, then identifies individual anatomical landmarks within a quadrant. (d) Four neural networks were trained, each with the objective of identifying a chest quadrant centroid. The four separate quadrants are visualized as colored boxes (right upper quadrant, green; right lower quadrant, blue; left upper quadrant, red; left lower quadrant, yellow). (e) Serial centroid then anatomical identification. Two quadrant examples showing confidence maps of trained neural networks identifying quadrant centroids (left) and then anatomical confidence maps (right). Image and caption courtesy of Chest Pulmonary.

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Image of patient (upper-left) in which, according to the radiologist's report, there is only consolidation, but the algorithm detects an abnormal rib (upper-right), consolidation (lower-left), and two nodules (lower-right). It is worth noting the confusion of a consolidation with mammary tissue and of two nodules with the two mammary areolae. Image courtesy of Scientific Reports.

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