Molecular Imaging Digital Community
FDA warns of risks with Lexiscan, Adenoscan stress agents
November 20, 2013 -- The U.S. Food and Drug Administration on November 20 issued a warning about a "rare but serious risk of heart attack and death" with the use of two cardiac nuclear stress test agents made by pharmaceutical developer Astellas.
PiB-PET shows more beta amyloid after traumatic brain injury
November 12, 2013 -- British researchers are using PET imaging with the Pittsburgh Compound B (PiB) radiopharmaceutical to show -- for the first time -- increased beta-amyloid deposits in cortical gray matter and striatum regions following traumatic brain injury.
PET/MRI could be alternative to PET/CT for liver lesions
October 28, 2013 -- PET/MRI is more than adequate in characterizing liver lesions and provides greater lesion conspicuity than PET/CT, offering clinicians a powerful alternative for oncology imaging, according to a German study published in the November issue of the European Journal of Radiology.
FDA approves GE's Vizamyl PET radiotracer for dementia
October 25, 2013 -- U.S. physicians looking to detect early signs of Alzheimer's disease now have a second tool in their arsenal with the U.S. Food and Drug Administration's approval of Vizamyl (flutemetamol F-18 injection), a radiopharmaceutical from GE Healthcare for use with PET imaging of the brain in adults being evaluated for Alzheimer's and dementia.
PiB-PET scans show link between poor sleep and Alzheimer's
October 22, 2013 -- PET scans using the Pittsburgh Compound B (PiB) radiopharmaceutical have shown a potential link between poor sleep and greater beta-amyloid accumulation, which could lead to Alzheimer's disease in older adults, according to a study published online October 21 in JAMA Neurology.
PET shows link between arterial stiffness and dementia
October 17, 2013 -- PET scans show that elderly people with hardening of the arteries are more likely to have beta-amyloid plaque in the brain, even if they show no signs of dementia or Alzheimer's disease, according to a study published online October 16 in Neurology.
Better training key to unlocking molecular imaging's potential
October 11, 2013 -- Molecular imaging has vast potential to improve healthcare in the coming years by allowing more directed, personalized therapy. But molecular imaging's contribution may be limited until more imaging specialists are trained to interpret scans acquired with the new types of tracers being developed.
ICER: Evidence of beta-amyloid PET's efficacy still lacking
October 1, 2013 -- A review of clinical studies on the efficacy of beta-amyloid PET for Alzheimer's disease has led the Institute for Clinical and Economic Review (ICER) to conclude that evidence supporting the scans is still lacking, according to an article published online September 30 in JAMA Internal Medicine.
PET/MRI shows growing edge over PET/CT in oncology
September 17, 2013 -- FDG-PET/MRI more accurately evaluated and more often changed the management of patients with various forms of cancer in a comparison with PET/CT, according to preliminary research published online September 5 in Radiology.
PET index predicts likelihood of dementia within 3 years
September 10, 2013 -- California researchers have developed a quantitative index based on functional brain data from PET scans to predict with a high degree of accuracy whether people with mild cognitive impairment will progress to dementia within three years.
PET/MRI helps with pulmonary nodule detection -- to a point
August 30, 2013 -- Simultaneous PET/MRI performs better than PET and MRI performed separately for the detection of FDG-avid pulmonary nodules and lesions at least 0.5 cm in size. However, it has problems with non-FDG-avid nodules and smaller lesions, researchers report in the September issue of Radiology.
Regadenoson with Rb-82 PET MPI helps detect obstructive CAD
August 16, 2013 -- The pharmacological stress agent regadenoson with rubidium-82 (Rb-82) PET myocardial perfusion imaging (MPI) has high sensitivity and diagnostic accuracy for detecting obstructive coronary artery disease (CAD), according to a study published online in the Journal of Nuclear Medicine.
Joint Commission seeks to expand imaging standards
August 15, 2013 -- The U.S. Joint Commission has proposed more-stringent requirements in the ambulatory care, critical access hospital, and hospital accreditation programs for facilities that provide CT, MRI, nuclear medicine, and PET services.
FDG-PET changes treatment, staging for Merkel cell carcinoma
August 14, 2013 -- Australian researchers found that FDG-PET scans changed the management plan for more than one-third of patients with Merkel cell carcinoma and altered the disease stage in approximately one in five cases, according to a study in the August issue of the Journal of Nuclear Medicine.
Study links triple-negative breast cancer on MRI, PET/CT scans
August 9, 2013 -- California researchers have found links between the appearance of triple-negative breast cancer on two different imaging modalities, MRI and PET/CT. They believe their findings can help guide therapy for the disease, which occurs less frequently but is typically more deadly than other types of breast cancer.
Report: U.S. SPECT, PET market looks promising in coming years
July 30, 2013 -- Powered by a number of new products and the potential of novel imaging agents currently in the pipeline, U.S. sales of SPECT and PET radiopharmaceuticals and scanners could top the billion-dollar mark by the next decade, according to a new market research report from Bio-Tech Systems.
Misdiagnosis of Alzheimer's can cost big money
July 23, 2013 -- Receiving a misdiagnosis of Alzheimer's disease can result in tens of thousands of dollars in unnecessary medical costs for patients who actually have vascular dementia or Parkinson's disease, according to a study presented on July 17 at the Alzheimer's Association International Conference in Boston.
NOPR leaves legacy of cancer coverage and cooperation
July 23, 2013 -- The seven-year initiative known as the National Oncologic PET Registry (NOPR) began to wind down its operation after the U.S. Centers for Medicare and Medicaid Services announced last month it would halt the data collection requirement for all oncologic indications for FDG-PET as a condition of reimbursement.
Florbetapir shows promise in detecting cardiac amyloid
July 16, 2013 -- Preliminary study results indicate that F-18 florbetapir (Amyvid) can detect cardiac amyloidosis, a buildup of protein that can lead to various forms of heart disease. The results hint that Amyvid could be useful beyond its core indication of detecting beta-amyloid deposits in the brain.
Florbetaben-PET detects amyloid in people with Down syndrome
July 11, 2013 -- A new study using PET with a florbetaben radiopharmaceutical shows how people with Down syndrome begin to accumulate beta-amyloid deposits in their brains in their early 40s, putting this population at greater risk for the early onset of cognitive impairment.
FDG-PET, DWI-MRI help predict osteosarcoma chemo response
July 11, 2013 -- Combining FDG-PET/CT and diffusion-weighed MRI (DWI-MRI) may be useful for predicting the histologic response of osteosarcoma to neoadjuvant chemotherapy, according to a study published in the July issue of the Journal of Nuclear Medicine.
GE recalls gamma cameras after fatal accident
July 9, 2013 -- In the wake of a fatal accident in which a patient was crushed by one of its gamma cameras, GE Healthcare has advised users of many of its nuclear medicine systems to stop using the products until they have been inspected by GE service engineers.
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