A Dutch study from Radbound University found that radiologists detected more lung nodules using ClearRead Bone Suppression 2.4 software than when they evaluated the chest x-ray images on their own. The study included 300 images (111 bone-suppressed x-rays with known lung nodules and 189 control cases without nodules). The radiologists detected 79% of the lung nodules with bone suppression compared with 71% without it.
Another study involving 300 bone-suppressed x-rays and eight readers at the same institution determined that using ClearRead +Detect 5.2 CAD software improved their performance. Radiologists accurately detected 79% of 111 lung nodules with CAD versus 73% without it. The software also found more than half of the nodules that the radiologists missed.
In a third study from the University of Chicago, ClearRead +Detect 5.2 CAD software detected 72% of lung nodules in 608 consecutive chest x-ray images without radiologist interpretation. It detected a majority of nodules on both portable and upright x-ray machines and even when other abnormalities were present.