SNMMI touts radioimmunotherapy study
Article Thumbnail ImageJuly 11, 2013 -- The Society of Nuclear Medicine and Molecular Imaging (SNMMI) is highlighting a Journal of Nuclear Medicine study that suggests a new radioimmunotherapy treatment option is safe and feasible for patients with relapsing follicular, mantle cell, and other indolent B-cell lymphomas.

To get access to this article and all of the content on AuntMinnie.com, create a free account or sign-in now.
(Helptag:PaywallArticleLoginMessage)
Member Sign In:
  MemberID or E-mail Address:
  Password:
(?)

New AuntMinnie.com Members

Becoming a Member is FREE!

  • Real-time radiology-specific news
  • Case of the Day and Teaching Files
  • Focused topics digital communities
  • Lively, discussion groups
  • Medical imaging bookstore
  • SalaryScan
  • Job Boards
  • Online CME
  • Bookstore, market reports, more …
  • Conference Calendar
  • User-controlled eNewsletters
  • … registration is FREE and easy!
  • The use of lutetium-177 (Lu-177) DOTA rituximab for radioimmunotherapy results in a high rate of tumor response with less radiation than current therapies, wrote lead author Dr. Andreas Lohri, from Kantonsspital Baselland in Switzerland, and colleagues (JNM, July 1, 2013, Vol. 54:7, pp. 1045-1052).

    The study included 31 patients with histologically confirmed relapsed or refractory CD20-positive B-cell lymphoma. All patients received an initial dose of Lu-177 DOTA rituximab; doses were increased in steps over a maximum of seven doses, and toxicity was measured weekly up to week 10 or until recovery from the lowest level of blood cell count. Imaging with whole-body CT and FDG-PET or PET/CT was conducted at baseline and again at eight to 12 weeks.

    The maximum tolerated dose using Lu-177 DOTA rituximab was 1,665 MBq/m2. Toxicity was mainly hematologic, with thrombocytopenia and leukopenia noted as the dose-limiting toxicities, and nonhematologic toxicity was minor, Lohri's group found.


    || About || Advertising || AuntMinnieCME.com || Bookstore || Breast MRI || Career Center || Case of the Day || Communities || Conferences || Contact Us || ECR News 2013 || Education || Equipment Classifieds || Europe || Facebook || Forums || Home || Links || Marketplace || Middle East || Mobile || Molecular Breast Imaging || New Installations || News in Brief || People in the News || Privacy Policy || RSNA News 2013 || Reference || Salary Survey Results || Trends in Radiology || Twitter || Vendor Connect || Webinars || XML/RSS ||

    Copyright © 2014 AuntMinnie.com. All Rights Reserved.