April 3, 2002 --
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Neoplastic disease of the pleura is more commonly the result of
dissemination than from primary tumor. Metastatic seeding of the pleura
is most commonly seen in lung, breast, ovarian, and gastrointestinal
carcinomas . Other tumors with a predilection for pleural spread
include thymomas, renal cell carcinomas, and melanoma . Pleural mets
often produce exudative
pleural effusions. Other findings indicative of malignant pleural
include the presence of focal, nodular pleural based masses,
pleural thickening, parietal pleural thickening greater than 1 cm, and
mediastinal pleural involvement.
Osteosarcoma: Osteosarcoma mets may coat or envelop the
It may mimic the appearance of pleural calcification caused by prior
or old hemothorax. Extension into the fissures may also occur.
(1) AJR 1997; Thoracic involvement from osteosarcoma: typical and
CT manifestations.168: 347-349 (no abstract available)
(2) AJR 2012; Makis W, et al. Spectrum of malignant pleural and
pericardial disease on FDG PET/CT. 198: 678-685