Frederic W. Grannis Jr.

CT
Do we need a better way to evaluate cardiac screening?
Although coronary artery disease is the number one cause of death in the U.S. today, there is no accepted screening test for the disease. Dr. Frederic Grannis wonders whether recent research studies are asking the right question.
September 7, 2022
2022 09 06 16 48 5734 Grannis Fred 20220906162207
CT
Shared decision-making: Is it harmful for lung cancer screening?
Why is CT lung cancer screening the only screening exam to require a session of shared decision-making between patients and doctors to receive Medicare reimbursement? Dr. Frederic Grannis examines this question in a new article.
April 13, 2021
2016 10 11 13 31 21 852 Am Second Opinion 400
CT
Is shared decision-making CT lung screening's Trojan horse?
Has the requirement that high-risk individuals complete a shared decision-making session with their doctors led to disappointing uptake of CT lung cancer screening? Dr. Frederic W. Grannis Jr. believes so, and, in fact, he sees shared decision-making as a deliberate attempt by opponents of screening to sabotage the exam -- much as the Trojan horse led to the downfall of Troy.
May 8, 2019
2016 10 11 13 31 21 852 Am Second Opinion 400
CT
Second Opinion: Medicare CT screening decision raises questions
"The large print giveth, but the small print taketh away." That quote by musician Tom Waits could well be applied to this week's decision approving Medicare payment for CT lung cancer screening, according to thoracic surgeon Dr. Frederic W. Grannis Jr., who believes that many people at risk of lung cancer may not get the scans they need.
November 12, 2014
2013 06 03 12 02 47 211 Second Opinion Am 200
CT
CT lung screening meeting: A travesty of public health policy
In retrospect, last week's negative vote by a Medicare panel against CT lung cancer screening is perhaps no surprise given the various conflicts of interest found among many members of the panel, according to Dr. Frederic W. Grannis Jr. Grannis attended the meeting and said he was stunned by the experience.
May 7, 2014
2013 06 03 12 02 47 211 Second Opinion Am 200
CT
Evidence is weak in NY Times editorial on radiation risk
On January 31, the New York Times published an op-ed on the cancer risks related to medical radiation. Titled "We are giving ourselves cancer," the article has produced an outpouring of commentary. In this response, thoracic surgeon Dr. Frederic W. Grannis Jr. questions whether the authors accurately portrayed the risks of medical radiation.
February 10, 2014
2013 05 31 15 04 19 427 Grannis Frederic 200 20140207223056
CT
What's causing the delay in CT lung screening guidelines?
A growing body of data points to the effectiveness of CT lung cancer screening. But clinicians are still waiting for national guidelines that will open the door to reimbursement for screening at-risk individuals. Thoracic surgeon Dr. Frederic W. Grannis Jr. wonders if the politics of CT screening is contributing to the delay.
June 2, 2013
2013 06 03 12 02 47 211 Second Opinion Am 200
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Images of a 39-year-old who underwent screening mammography. Right craniocaudal (left) and mediolateral oblique (middle) views from preoperative mammography show suspicious grouped fine pleomorphic calcifications (arrows). After biopsy showed ductal carcinoma of situ (DCIS), patient underwent breast-conserving surgery, yielding final diagnosis of ductal carcinoma in situ (intermediate grade, hormone receptor positive). (Right) Screenshot of an output of a commercial AI tool applied to preoperative mammography. AI detected right breast lesion with score of 95% on both views (concentric colored circles). Present study’s reviewing radiologist deemed AI marking to correspond with site of DCIS.
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Images from two representative cases. (A-C) Images in an 82-year-old man with a calcified plaque in the proximal segment of the left anterior descending artery. (A, B) Curved planar reconstruction images from CCTA with (A) hybrid iterative reconstruction (HIR) and (B) super-resolution deep learning reconstruction (SR-DLR) show that the measured PDS was 66% for the HIR image and 42% for the SR-DLR image. (C) Quantitative analysis of the invasive coronary angiography (ICA) image (reference standard) revealed a PDS of 34% (arrow). (D-F) Images in a 37-year-old woman with a noncalcified plaque in the middle segment of the left circumflex artery. (D, E) Curved planar reconstruction images from CCTA with (D) HIR and (E) SR-DLR show that the measured PDS was 47% for the HIR image and 80% for the SR-DLR image. (F) Quantitative analysis of the ICA image revealed a PDS of 72% (arrow). Blue, red, and yellow lines in A, B, D, and E represent the proximal reference point, stenosed lesion, and distal reference point, respectively, and the insets show the corresponding cross-sectional images.
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